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DESU Modeling and simulation: physiologically-based pharmacokinetic modelling for pharmacology and toxicology

  • DESU
  • Initial training, continuing education
  • Hybrid
  • 100-120h over 4 (non-consecutive) weeks

Pharmacometrics is a rapidly evolving and growing field. There is an urgent need of trained experts capable of developing and applying PBPK models with various purposes, such as R&D of new pharmaceuticals, inter-individual variability handling and assessment of toxicological risks. This course will give you the theoretical and technical knowledge to accurately develop, apply and evaluate PBPK models.

  • Objectives

    The objective of the course is for the attendees to master the concepts and the in silico tools for PBPK models. For more details, please refer to the two courses included in the current training: "Fundamentals for modeling and simulation in pharmacokinetics/pharmacodynamics" and "Advanced course in physiologically-based pharmacokinetic modeling"

  • Organisation of the training

    The course will last over 4 weeks: 2 weeks for the course "Fundamentals for modeling and simulation in pharmacokinetics/pharmacodynamics" followed by 2 weeks for the course "Advanced course in physiologically-based pharmacokinetic modeling" (See these courses for details). The 100-120 hours of teaching will be divided in 50% theory and 50% hands-ons on usual mathematical and pharmacometrics softwares. The last day of each course will be devoted to an evaluation of the acquired skills

  • Further education

    The course is intended to post-graduate students or professionals and will lead to the delivery of the university diploma "Modeling and simulation: physiologically-based pharmacokinetic modelling for pharmacology and toxicology", which will certify an advanced level in population modeling, which is sought for various positions in the pharmaceutical industry and in regulatory drugs or toxicology agencies.

  • Admission conditions

    A preliminary knowledge of pharmacokinetics is a pre-requisite. Scientific bases (mathematics, biology, chemistry) are also needed.

  • Partnership

    The course will be animated by diverse recognized experts of each subject, professionals from the academia (French and international) and from the industry (Pharma companies, CROs).

  • Other information

    The courses will be taught in English.

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Florence
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GATTACCETA